Curse you, Perry the Platypus! is the one of the most notable running gags and catchphrases.
When Doofenshmirtz is defeated, he yells "Curse you, Perry the Platypus!" before the end of an episode.
Dr. Doofenshmirtz: It's no use, it's no use, we are doomed! You did it! You saved us, Perry the...(Tin foil ball crashes into the building)
Dr. Doofenshmirtz: Curse you, Perry the Platypus!
Doofenshmirtz: AAH! (Perry locks the Drill-inator's target onto the Old Reliable Geyser and jumps off) Wait, where are you going? AAH! (The Drill-inator lands on the geyser) I'm okay, I -- (spins around and gets flung away) AAH! Fie upon you, Perry the Platypuuuuus!
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