Esmeralda Poofenplotz



"I can't very well take over the world until I'm drop-dead gorgeous."

- Prof. Poofenplotz

 is the nemesis of Agent Pinky, Isabella Garcia-Shapiro's dog. ("Day of the Living Gelatin", "Isabella and the Temple of Sap")

Her known schemes so far involve replacing handbags and searching for strong hairspray.

She is concerned about her looks, as she can't take over the world until she feels she looks her best. Otherwise she shares much of Dr. Doofenshmirtz's personality, including having a vehicle which has her head as the main body.

She has a mechanical spider shaped like her head and carries around a ray gun what sends people to another dimension.

Her evil jingle:

Poofenplotz Evil is Crazy